Biosensors 2025年生物传感器材料栏目文章精选主编荐读。期刊名：Biosensors
期刊主页：https://www.mdpi.com/journal/biosensors
随着先进纳米材料、功能高分子与仿生界面的不断突破，生物传感材料正从传统的单一响应/被动识别迈向高灵敏、多模态、智能催化、可集成的新范式。本文献清单荟萃了发表于 Biosensors 的一批具有代表性的工作，系统梳理了新型传感材料的设计策略及其在复杂体系中的应用潜力。内容涵盖了从碳量子点、MXene量子点及复合纳米颗粒等新型信号放大材料，到面向癌症标志物、病原体与食品安全的高灵敏检测方案；从MOF基纳米酶与核酸纳米酶构筑的智能催化识别网络，到分子印迹聚合物（MIPs）实现的特异性分子捕获；同时也关注微流控液滴操控、SERS/等离激元增强平台、高盐体液电容式检测等跨学科技术，以及无线集成传感与深度学习多模态融合的前沿探索。这些成果串联起了从材料理性设计到精准信号转换的完整技术链条，为下一代临床即时诊断、环境健康监测与智慧医疗的应用提供了更多参考。
1. Carbon Quantum Dots: Synthesis, Characteristics, and Quenching as Biocompatible Fluorescent Probes
碳量子点：作为生物相容性荧光探针的合成、特性及猝灭行为
https://www.mdpi.com/2079-6374/15/2/99
Kamal, A.; Hong, S.; Ju, H. Carbon Quantum Dots: Synthesis, Characteristics, and Quenching as Biocompatible Fluorescent Probes. Biosensors 2025, 15, 99. https://doi.org/10.3390/bios15020099
2. Electrochemical Impedance Spectroscopy-Based Biosensors for Label-Free Detection of Pathogens
基于电化学阻抗谱的病原体无标记检测生物传感器
https://www.mdpi.com/2079-6374/15/7/443
Zhang, H.; Sun, Z.; Sun, K.; Liu, Q.; Chu, W.; Fu, L.; Dai, D.; Liang, Z.; Lin, C.-T. Electrochemical Impedance Spectroscopy-Based Biosensors for Label-Free Detection of Pathogens. Biosensors 2025, 15, 443. https://doi.org/10.3390/bios15070443
3. Comprehensive Analysis of Advancement in Optical Biosensing Techniques for Early Detection of Cancerous Cells
用于癌症细胞早期检测的光学生物传感技术进展的综合分析
https://www.mdpi.com/2079-6374/15/5/292
Ramola, A.; Shakya, A.K.; Bergman, A. Comprehensive Analysis of Advancement in Optical Biosensing Techniques for Early Detection of Cancerous Cells. Biosensors 2025, 15, 292. https://doi.org/10.3390/bios15050292
4. Colorimetric Biosensors: Advancements in Nanomaterials and Cutting-Edge Detection Strategies
比色生物传感器：纳米材料的进展与前沿检测策略
https://www.mdpi.com/2079-6374/15/6/362
Lee, Y.; Haizan, I.; Sim, S.B.; Choi, J.-H. Colorimetric Biosensors: Advancements in Nanomaterials and Cutting-Edge Detection Strategies. Biosensors 2025, 15, 362. https://doi.org/10.3390/bios15060362
5. Droplet Generation and Manipulation in Microfluidics: A Comprehensive Overview of Passive and Active Strategies
微流控中的液滴生成与操控：被动与主动策略的综合综述
https://www.mdpi.com/2079-6374/15/6/345
Fergola, A.; Ballesio, A.; Frascella, F.; Napione, L.; Cocuzza, M.; Marasso, S.L. Droplet Generation and Manipulation in Microfluidics: A Comprehensive Overview of Passive and Active Strategies. Biosensors 2025, 15, 345. https://doi.org/10.3390/bios15060345
6. Recent Advances in Metal–Organic Framework-Based Nanozymes for Intelligent Microbial Biosensing: A Comprehensive Review of Biomedical and Environmental Applications
基于金属有机框架的纳米酶用于智能微生物生物传感的最新进展：生物医学与环境应用综述
https://www.mdpi.com/2079-6374/15/7/437
Kidanemariam, A.; Cho, S. Recent Advances in Metal–Organic Framework-Based Nanozymes for Intelligent Microbial Biosensing: A Comprehensive Review of Biomedical and Environmental Applications. Biosensors 2025, 15, 437. https://doi.org/10.3390/bios15070437
7. Small Toxic Molecule Detection and Elimination Using Molecularly Imprinted Polymers (MIPs)
利用分子印迹聚合物（MIPs）检测与去除小分子毒物
https://www.mdpi.com/2079-6374/15/6/393
Kang, M.S.; Lee, J.-H.; Kim, K.S. Small Toxic Molecule Detection and Elimination Using Molecularly Imprinted Polymers (MIPs). Biosensors 2025, 15, 393. https://doi.org/10.3390/bios15060393
8. Recent Advances in Electrochemical Sensors for the Detection of Anti-Inflammatory and Antibiotic Drugs: A Comprehensive Review
用于检测抗炎药和抗生素药物的电化学传感器研究进展：综合综述
https://www.mdpi.com/2079-6374/15/10/676
Mello, G.A.B.; Benjamin, S.R.; de Lima, F.; Dutra, R.F. Recent Advances in Electrochemical Sensors for the Detection of Anti-Inflammatory and Antibiotic Drugs: A Comprehensive Review. Biosensors 2025, 15, 676. https://doi.org/10.3390/bios15100676
9. Exploring Nucleic Acid Nanozymes: A New Frontier in Biosensor Development
探索核酸纳米酶：生物传感器开发的新前沿
https://www.mdpi.com/2079-6374/15/3/142
Chen, K.; Du, Z.; Zhang, Y.; Bai, R.; Zhu, L.; Xu, W. Exploring Nucleic Acid Nanozymes: A New Frontier in Biosensor Development. Biosensors 2025, 15, 142. https://doi.org/10.3390/bios15030142
10. Aptamer-Conjugated Multi-Quantum Dot-Embedded Silica Nanoparticles for Lateral Flow Immunoassay
用于侧向层析免疫分析的适配体偶联多量子点包埋二氧化硅纳米颗粒
https://www.mdpi.com/2079-6374/15/1/54
Yoo, K.; Cho, H.-S.; Kim, J.; Shin, M.; Chu, J.-S.; Jang, S.; Bae, H.-J.; Jung, H.S.; Kang, H.; Jun, B.-H. Aptamer-Conjugated Multi-Quantum Dot-Embedded Silica Nanoparticles for Lateral Flow Immunoassay. Biosensors 2025, 15, 54. https://doi.org/10.3390/bios15010054
11. A Sensitive Electrochemical Cholinesterase-Inhibiting Biosensor for Organophosphorus Pesticides Based on Ti3C2TX MXene Quantum Dots
基于 Ti3C2Tx MXene 量子点的有机磷农药高灵敏电化学胆碱酯酶抑制生物传感器
https://www.mdpi.com/2079-6374/15/9/575
Makani, N.; Wu, J.; Florentino, J.; Chafin, C.F.; Gautam, B.; Chao, S.; Han, S. A Sensitive Electrochemical Cholinesterase-Inhibiting Biosensor for Organophosphorus Pesticides Based on Ti3C2TX MXene Quantum Dots. Biosensors 2025, 15, 575. https://doi.org/10.3390/bios15090575
12. On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery
关于基于SERS监测靶向递送外泌体载药效率可行性的研究
https://www.mdpi.com/2079-6374/15/3/141
Liu, J.; Srivastava, S.; Li, T.; Moujane, F.; Lee, J.Y.; Chen, Y.; Liu, H.; Deng, S.X.; Xie, Y.-H. On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. Biosensors 2025, 15, 141. https://doi.org/10.3390/bios15030141
13. Deep Learning-Driven Multimodal Integration of miRNA and Radiomic for Lung Cancer Diagnosis
基于深度学习的肺癌诊断：miRNA与影像组学的多模态融合
https://www.mdpi.com/2079-6374/15/9/610
Chen, Y.; Chen, D.; Liu, X.; Jiang, H.; Wang, X. Deep Learning-Driven Multimodal Integration of miRNA and Radiomic for Lung Cancer Diagnosis. Biosensors 2025, 15, 610. https://doi.org/10.3390/bios15090610
14. Plasmonic Biosensors in Cancer-Associated miRNA Detection
用于癌症相关 miRNA 检测的等离激元生物传感器
https://www.mdpi.com/2079-6374/15/3/165
Kim, N.; Bae, M.; Cho, E.; Kim, K.S.; Lee, J.-H. Plasmonic Biosensors in Cancer-Associated miRNA Detection. Biosensors 2025, 15, 165. https://doi.org/10.3390/bios15030165
15. Capacitive Sensors for Label-Free Detection in High-Ionic-Strength Bodily Fluids: A Review
用于高离子强度体液中无标记检测的电容式传感器：综述
https://www.mdpi.com/2079-6374/15/8/491
Sekhon, S.; Bayford, R.; Demosthenous, A. Capacitive Sensors for Label-Free Detection in High-Ionic-Strength Bodily Fluids: A Review. Biosensors 2025, 15, 491. https://doi.org/10.3390/bios15080491
16. Aptamer-Conjugated Magnetic Nanoparticles Integrated with SERS for Multiplex Salmonella Detection
结合SERS的适配体偶联磁性纳米颗粒用于沙门氏菌多重检测
https://www.mdpi.com/2079-6374/15/7/464
Sun, F.; Pang, K.; Yang, K.; Zheng, L.; Wang, M.; Wang, Y.; Chen, Q.; Ye, Z.; Liang, P.; Yu, X. Aptamer-Conjugated Magnetic Nanoparticles Integrated with SERS for Multiplex Salmonella Detection. Biosensors 2025, 15, 464. https://doi.org/10.3390/bios15070464
17. A High-Sensitivity, Bluetooth-Enabled PCB Biosensor for HER2 and CA15-3 Protein Detection in Saliva: A Rapid, Non-Invasive Approach to Breast Cancer Screening
一种用于检测唾液中 HER2 和 CA15-3 蛋白的高灵敏度蓝牙 PCB 生物传感器：一种乳腺癌筛查的快速、无创方法
https://www.mdpi.com/2079-6374/15/6/386
Wan, H.-H.; Chiang, C.-C.; Ren, F.; Tsai, C.-T.; Chou, Y.-S.; Chiu, C.-W.; Liao, Y.-T.; Neal, D.; Heldermon, C.D.; Rocha, M.G.; et al. A High-Sensitivity, Bluetooth-Enabled PCB Biosensor for HER2 and CA15-3 Protein Detection in Saliva: A Rapid, Non-Invasive Approach to Breast Cancer Screening. Biosensors 2025, 15, 386. https://doi.org/10.3390/bios15060386
18. Wearable Ultrasound-Imaging-Based Visual Feedback (UVF) Training for Ankle Rehabilitation of Chronic Stroke Survivors: A Proof-of-Concept Randomized Crossover Study
基于可穿戴超声成像视觉反馈（UVF）的慢性脑卒中幸存者踝关节康复训练：一项概念验证随机交叉研究
https://www.mdpi.com/2079-6374/15/6/365
Luo, Y.-Y.; Huang, C.; Song, Z.; Nazari, V.; Wong, A.Y.-L.; Yang, L.; Dong, M.; Zhang, M.; Zheng, Y.-P.; Fu, A.S.-N.; et al. Wearable Ultrasound-Imaging-Based Visual Feedback (UVF) Training for Ankle Rehabilitation of Chronic Stroke Survivors: A Proof-of-Concept Randomized Crossover Study. Biosensors 2025, 15, 365. https://doi.org/10.3390/bios15060365
19. Sensing Protein Structural Transitions with Microfluidic Modulation Infrared Spectroscopy
利用微流控调制红外光谱检测蛋白质结构转变
https://www.mdpi.com/2079-6374/15/6/382
Lucas, L.; Tsoi, P.S.; Nair, A.; Ferreon, A.C.M.; Ferreon, J.C. Sensing Protein Structural Transitions with Microfluidic Modulation Infrared Spectroscopy. Biosensors 2025, 15, 382. https://doi.org/10.3390/bios15060382
20. Exhaled Aldehydes and Ketones as Biomarkers of Lung Cancer and Diabetes: Review of Sensor Technologies for Early Disease Diagnosis
作为肺癌和糖尿病生物标志物的呼出气醛类与酮类：疾病早期诊断传感器技术综述
https://www.mdpi.com/2079-6374/15/10/668
Kiejzik, R.; Wasilewski, T.; Kamysz, W. Exhaled Aldehydes and Ketones as Biomarkers of Lung Cancer and Diabetes: Review of Sensor Technologies for Early Disease Diagnosis. Biosensors 2025, 15, 668. https://doi.org/10.3390/bios15100668
期刊介绍
主编：Prof. Dr. Giovanna Marrazza
Biosensors（ISSN 2079-6374）为生物传感器及生物传感相关科学与技术领域的研究提供了一个高水平的交流平台。该期刊发表原创性研究论文、综合性综述及简报。我们旨在鼓励科学家尽可能详尽地发表其实验与理论研究成果。论文篇幅不设上限，但必须提供完整的实验细节，以确保研究结果可被复现。
2025 Impact Factor：6.2
2025 CiteScore：12.1
Time to First Decision：17.3 Days
Acceptance to Publication：2.9 Days
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来源：Biosensors
